|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (2.5 µg/ml), WB (0.5-1 µg/ml),|
|Other Names||Inactive caspase-12, CASP-12, CASP12|
|Target/Specificity||peptide corresponding to amino acids 100 to 116 of murine caspase-12|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||CASP12 / Caspase 12 Antibody (aa100-116) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.|
|Tissue Location||Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis|
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Provided below are standard protocols that you may find useful for product applications.
Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.
Fischer H.,et al.Biochem. Biophys. Res. Commun. 293:722-726(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Taylor T.D.,et al.Nature 440:497-500(2006).
Saleh M.,et al.Nature 429:75-79(2004).
Kachapati K.,et al.Hum. Mutat. 27:975-975(2006).
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