|Application ||IHC-P, IF|
|Reactivity||Human, Mouse, Rat, Rabbit, Monkey, Chicken, Sheep, Horse, Bovine, Dog|
|Other Names||Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2|
|Target/Specificity||Recognizes the cardiac isoform of rabbit Troponin T (cTnT). Species cross-reactivity: Canine, chicken, goldfish, guinea pig, human, mouse, porcine, rat, sparrow. Does not react with frog.|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||TNNT2 / CTNT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.|
|Tissue Location||Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Mesnard L.,et al.FEBS Lett. 328:139-144(1993).
Townsend P.J.,et al.Genomics 21:311-316(1994).
Townsend P.J.,et al.J. Mol. Cell. Cardiol. 27:2223-2236(1995).
Anderson P.A.,et al.Circ. Res. 76:681-686(1995).
Mesnard L.,et al.Circ. Res. 76:687-692(1995).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.