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TNNT2 / CTNT Antibody
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IF |
|---|---|
| Primary Accession | P45379 |
| Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Chicken, Sheep, Horse, Bovine, Dog |
| Host | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 36kDa |
| Dilution | IHC-P (1:50) |
| Gene ID | 7139 |
|---|---|
| Other Names | Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2 |
| Target/Specificity | Recognizes the cardiac isoform of rabbit Troponin T (cTnT). Species cross-reactivity: Canine, chicken, goldfish, guinea pig, human, mouse, porcine, rat, sparrow. Does not react with frog. |
| Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Precautions | TNNT2 / CTNT Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNNT2 |
|---|---|
| Function | Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Tissue Location | Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
References
Mesnard L.,et al.FEBS Lett. 328:139-144(1993).
Townsend P.J.,et al.Genomics 21:311-316(1994).
Townsend P.J.,et al.J. Mol. Cell. Cardiol. 27:2223-2236(1995).
Anderson P.A.,et al.Circ. Res. 76:681-686(1995).
Mesnard L.,et al.Circ. Res. 76:687-692(1995).
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