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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ROR1 Antibody   

ROR1 Antibody

Goat Polyclonal Antibody

     
  • IHC - ROR1 Antibody ALS12922
    Anti-ROR1 antibody IHC of human liver.
  • IHC - ROR1 Antibody ALS12922
    Anti-ROR1 antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q01973
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 104kDa
Dilution IHC-P (3-6 µg/ml)
Additional Information
Gene ID 4919
Other Names Tyrosine-protein kinase transmembrane receptor ROR1, 2.7.10.1, Neurotrophic tyrosine kinase, receptor-related 1, ROR1, NTRKR1
Target/Specificity Human ROR1. This antibody is expected to recognize isoform 1 (NP_005003.2) only.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsROR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ROR1
Synonyms NTRKR1
Function Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A- mediated signaling.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm
Research Areas
Citations (0)

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Background

Tyrosine-protein kinase receptor whose role is not yet clear.

References

Masiakowski P.,et al.J. Biol. Chem. 267:26181-26190(1992).
Reddy U.R.,et al.Oncogene 13:1555-1559(1996).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Sjoeblom T.,et al.Science 314:268-274(2006).

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$ 395.00
Cat# ALS12922
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