|Application ||IHC-P, E|
|Reactivity||Human, Mouse, Rat, Hamster, Monkey, Pig, Sheep, Horse, Bovine, Dog|
|Dilution||IHC-P (3-6 µg/ml)|
|Other Names||Calponin-1, Basic calponin, Calponin H1, smooth muscle, CNN1|
|Target/Specificity||Human CNN1 / Calponin.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||CNN1 / Calponin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).|
|Tissue Location||Smooth muscle, and tissues containing significant amounts of smooth muscle|
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Provided below are standard protocols that you may find useful for product applications.
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
Maguchi M.,et al.Biochem. Biophys. Res. Commun. 217:238-244(1995).
Miano J.M.,et al.Gene 197:215-224(1997).
Takahashi K.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
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