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ICAM3 / CD50 Antibody (clone MEM-04, Azide-free)

Mouse Monoclonal Antibody

     
  • IHC - ICAM3 / CD50 Antibody (clone MEM-04, Azide-free) ALS12926
    Anti-ICAM3 antibody IHC staining of human spleen.
  • IHC - ICAM3 / CD50 Antibody (clone MEM-04, Azide-free) ALS12926
    Anti-ICAM3 antibody IHC staining of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo, Func
Primary Accession P32942
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names MEM-04
Calculated MW 60kDa
Dilution Func, IHC-P (10 µg/ml),
Additional Information
Gene ID 3385
Other Names Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
Target/Specificity Reacts with CD50 (ICAM-3), a 120-130 kD type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes. The MEM-04 blocks DC-SIGN (CD209) binding ...
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsICAM3 / CD50 Antibody (clone MEM-04, Azide-free) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ICAM3
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Leukocytes.
Research Areas
Citations (0)

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Background

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.

References

Fawcett J.,et al.Nature 360:481-484(1992).
Vazeux R.,et al.Nature 360:485-488(1992).
de Fougerolles A.R.,et al.J. Exp. Med. 177:1187-1192(1993).
Tan J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS12926
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