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LCP2 / SLP-76 Antibody (aa216-434)

Rabbit Polyclonal Antibody

     
  • IHC - LCP2 / SLP-76 Antibody (aa216-434) ALS12936
    Anti-LCP2 / SLP-76 antibody IHC of human thymus.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q13094
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 60kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 3937
Other Names Lymphocyte cytosolic protein 2, SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, SLP76, LCP2
Target/Specificity The polyclonal antibody reacts with SLP76, a 76kDa cytosolic adaptor protein that is involved in signaling of various hematopoietic cells, such as T cells, mast cells or neutrophils; in B cells, however, it is replaced by SLP65.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsLCP2 / SLP-76 Antibody (aa216-434) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LCP2
Function Involved in T-cell antigen receptor mediated signaling.
Cellular Location Cytoplasm.
Tissue Location Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines
Research Areas
Citations (0)
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Background

Involved in T-cell antigen receptor mediated signaling.

References

Jackman J.K.,et al.J. Biol. Chem. 270:7029-7032(1995).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Moog-Lutz C.,et al.J. Biol. Chem. 276:22375-22381(2001).

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Discontinued
Cat# ALS12936
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