|Application ||WB, IHC-P, IP|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Bovine, Dog|
|Dilution||IHC-P (10 µg/ml), WB (0.5 µg/ml),|
|Other Names||Amphiphysin, AMPH, AMPH1|
|Target/Specificity||Detects a ~128 kD protein, corresponding to the apparent molecular mass of Amphiphysin I on SDS-PAGE immunoblots, in samples from human, mouse, rat, bovine, canine, hamster, monkey and rabbit origins. A 108 kD isoform may be observed in some tissues ...|
|Reconstitution & Storage||Store at -20°C.|
|Precautions||AMPH / Amphiphysin Antibody (clone 3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton|
|Tissue Location||Neurons, certain endocrine cell types and spermatocytes|
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Provided below are standard protocols that you may find useful for product applications.
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
David C.,et al.FEBS Lett. 351:73-79(1994).
Yamamoto R.,et al.Hum. Mol. Genet. 4:265-268(1995).
Floyd S.R.,et al.Mol. Med. 4:29-39(1998).
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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