|Application ||WB, IHC-P, IP|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Bovine, Dog|
|Dilution||IHC-P (10 µg/ml), WB (0.5 µg/ml),|
|Other Names||Amphiphysin, AMPH, AMPH1|
|Target/Specificity||Detects a ~128 kD protein, corresponding to the apparent molecular mass of Amphiphysin I on SDS-PAGE immunoblots, in samples from human, mouse, rat, bovine, canine, hamster, monkey and rabbit origins. A 108 kD isoform may be observed in some tissues ...|
|Reconstitution & Storage||Store at -20°C.|
|Precautions||AMPH / Amphiphysin Antibody (clone 3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton|
|Tissue Location||Neurons, certain endocrine cell types and spermatocytes|
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May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
David C.,et al.FEBS Lett. 351:73-79(1994).
Yamamoto R.,et al.Hum. Mol. Genet. 4:265-268(1995).
Floyd S.R.,et al.Mol. Med. 4:29-39(1998).
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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