|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog|
|Dilution||IHC-P (3.75 µg/ml)|
|Other Names||Transcriptional repressor p66-beta, GATA zinc finger domain-containing protein 2B, p66/p68, GATAD2B, KIAA1150|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||GATAD2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.|
|Cellular Location||Nucleus speckle. Note=Speckled nuclear localization requires both CR1 and CR2 regions|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.
Feng Q.,et al.Mol. Cell. Biol. 22:536-546(2002).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Hirosawa M.,et al.DNA Res. 6:329-336(1999).
Brackertz M.,et al.J. Biol. Chem. 277:40958-40966(2002).
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