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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RASSF2 Antibody   

RASSF2 Antibody

Goat Polyclonal Antibody

     
  • IHC - RASSF2 Antibody ALS12987
    Anti-RASSF2 antibody IHC of human liver.
  • IHC - RASSF2 Antibody ALS12987
    Anti-RASSF2 antibody IHC of human spleen.
  • IHC - RASSF2 Antibody ALS12987
    Anti-RASSF2 antibody IHC of human thymus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P50749
Reactivity Human, Rabbit, Monkey, Pig, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 38kDa
Dilution IHC-P (3.75 µg/ml)
Additional Information
Gene ID 9770
Other Names Ras association domain-containing protein 2, RASSF2, KIAA0168
Target/Specificity Human RASSF2. Reported variants represent identical protein: NP_055552.1; NP_739580.1.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsRASSF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RASSF2
Synonyms CENP-34 {ECO:0000303|PubMed:20813266}, K
Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Cellular Location Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1
Tissue Location Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Research Areas
Citations (0)

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Background

Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.

References

Burbee D.G.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 3:17-24(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 395.00
Cat# ALS12987
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