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RASSF2 Antibody
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P50749 |
| Reactivity | Human, Rabbit, Monkey, Pig, Horse, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 38kDa |
| Dilution | IHC-P (3.75 µg/ml) |
| Gene ID | 9770 |
|---|---|
| Other Names | Ras association domain-containing protein 2, RASSF2, KIAA0168 |
| Target/Specificity | Human RASSF2. Reported variants represent identical protein: NP_055552.1; NP_739580.1. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | RASSF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RASSF2 |
|---|---|
| Synonyms | CENP-34 {ECO:0000303|PubMed:20813266}, K |
| Function | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. |
| Cellular Location | Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 and STK4/MST1 |
| Tissue Location | Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
References
Burbee D.G.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 3:17-24(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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