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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AKIRIN2 Antibody (Internal)   

AKIRIN2 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • WB - AKIRIN2 Antibody (Internal) ALS12988
    Western blot of Akirin2 in Human Brain tissue lysate with Akirin2 antibody at 0.5 ug/ml in (A)...
  • IHC - AKIRIN2 Antibody (Internal) ALS12988
    Anti-AKIRIN2 antibody IHC of human skin.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q53H80
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 22kDa
Dilution IHC-P (5 µg/ml), WB (0.5 µg/ml),
Additional Information
Gene ID 55122
Other Names Akirin-2, AKIRIN2, C6orf166
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsAKIRIN2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKIRIN2
Synonyms C6orf166
Function Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).
Cellular Location Nucleus.
Tissue Location Widely expressed with the highest expression in peripheral blood leukocytes.
Research Areas
Citations (0)

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Background

Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).

References

Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Olsen J.V.,et al.Cell 127:635-648(2006).
Goto A.,et al.Nat. Immunol. 9:97-104(2008).
Goto A.,et al.Nat. Immunol. 9:216-216(2008).

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$ 395.00
Cat# ALS12988
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