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GLE1 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IF - GLE1 Antibody (Internal) ALS13019
    Immunofluorescence of gle1 in mouse brain tissue with gle1 antibody at 20 ug/ml.
    detail
  • IHC - GLE1 Antibody (Internal) ALS13019
    Anti-GLE1 / GLE1L antibody IHC of human adrenal.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q53GS7
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 80kDa
Dilution IHC-P (10 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 2733
Other Names Nucleoporin GLE1, hGLE1, GLE1-like protein, GLE1, GLE1L
Target/Specificity At least three isoforms of Gle1 are known to exist.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsGLE1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLE1
Synonyms GLE1L
Function Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
Cellular Location Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm (PubMed:12668658). Shuttling is essential for its mRNA export function (PubMed:12668658).
Research Areas
Citations (0)
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Background

Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).

References

Watkins J.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:6779-6784(1998).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Kendirgi F.,et al.J. Cell Biol. 160:1029-1040(2003).

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Discontinued
Cat# ALS13019
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