|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (0.5-1 µg/ml),|
|Other Names||Spatacsin, Colorectal carcinoma-associated protein, Spastic paraplegia 11 protein, SPG11, KIAA1840|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||KIAA1840 / SPG11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport.|
|Cellular Location||Cytoplasm, cytosol. Nucleus. Cell projection, axon. Cell projection, dendrite. Note=Mainly cytoplasmic|
|Tissue Location||Expressed in all structures of brain, with a high expression in cerebellum. Expressed in cortical projection neurons.|
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Provided below are standard protocols that you may find useful for product applications.
Nagase T.,et al.DNA Res. 8:85-95(2001).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Zody M.C.,et al.Nature 440:671-675(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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