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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SH3BP1 Antibody (C-Terminus)   

SH3BP1 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - SH3BP1 Antibody (C-Terminus) ALS13074
    Anti-SH3BP1 antibody IHC of human spleen.
  • IHC - SH3BP1 Antibody (C-Terminus) ALS13074
    Anti-SH3BP1 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9Y3L3
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 76kDa
Dilution ELISA (1:16000), IHC-P (2.5 µg/ml), WB (1-3 µg/ml)
Additional Information
Gene ID 23616
Other Names SH3 domain-binding protein 1, 3BP-1, SH3BP1
Target/Specificity Human SH3BP1.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsSH3BP1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH3BP1
Function Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).
Research Areas
Citations (0)

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Background

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).

References

Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Carrascal M.,et al.J. Proteome Res. 7:5167-5176(2008).

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$ 395.00
Cat# ALS13074
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