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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PDE4D Antibody (C-Terminus)   

PDE4D Antibody (C-Terminus)

Goat Polyclonal Antibody

  • WB - PDE4D Antibody (C-Terminus) ALS13083
    Antibody staining (1 ug/ml) of COS cell lysates (25 ug protein): transfected with Human PDE4D1...
  • IHC - PDE4D Antibody (C-Terminus) ALS13083
    Anti-PDE4D antibody IHC of human heart.
  • IHC - PDE4D Antibody (C-Terminus) ALS13083
    Anti-PDE4D antibody IHC of human skeletal muscle.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08499
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 91kDa
Dilution ELISA (1:128000), IHC-P (5 µg/ml), WB (0.1-1 µg/ml)
Additional Information
Gene ID 5144
Other Names cAMP-specific 3', 5'-cyclic phosphodiesterase 4D,, DPDE3, PDE43, PDE4D, DPDE3
Target/Specificity Human PDE4D. This antiobody is expected to recognize all reported isoforms.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsPDE4D Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDE4D
Synonyms DPDE3
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Cellular Location Apical cell membrane. Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome (By similarity). Colocalized with SHANK2 to the apical membrane of colonic crypt cells.
Tissue Location Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
Research Areas
Citations (0)

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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.


Bolger G.,et al.Mol. Cell. Biol. 13:6558-6571(1993).
Nemoz G.,et al.FEBS Lett. 384:97-102(1996).
Baecker P.A.,et al.Gene 138:253-256(1994).
Bolger G.B.,et al.Biochem. J. 328:539-548(1997).
Miro X.,et al.Biochem. Biophys. Res. Commun. 274:415-421(2000).

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$ 395.00
Cat# ALS13083
(40 western blots)
Availability: 5 days
Bulk Size
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