|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:8000), IHC-P (5 µg/ml), WB (1:8000)|
|Other Names||cAMP-specific 3', 5'-cyclic phosphodiesterase 4B, 184.108.40.206, DPDE4, PDE32, PDE4B, DPDE4|
|Target/Specificity||Human PDE4B. This antibody is expected to recognise all reported isoforms (NP_002591.2, NP_001032418.1, NP_001032416.1 and NP_001032417.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||PDE4B Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.|
|Tissue Location||Expressed in brain, heart, lung and skeletal muscle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Obernolte R.,et al.Gene 129:239-247(1993).
Bolger G.,et al.Mol. Cell. Biol. 13:6558-6571(1993).
Huston E.,et al.Biochem. J. 328:549-558(1997).
McLaughlin M.M.,et al.J. Biol. Chem. 268:6470-6476(1993).
Cheung Y.F.,et al.J. Pharmacol. Exp. Ther. 322:600-609(2007).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.