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IGFBP6 Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - IGFBP6 Antibody (Internal) ALS13104
    Antibody (0.5 ug/ml) staining of Human Adrenal Gland lysate (35 ug protein in RIPA buffer).
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P24592
Reactivity Human, Dog
Host Goat
Clonality Polyclonal
Calculated MW 25kDa
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (0.5-1.5 µg/ml)
Additional Information
Gene ID 3489
Other Names Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6, IGFBP6, IBP6
Target/Specificity Human IGFBP6.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsIGFBP6 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGFBP6 (HGNC:5475)
Synonyms IBP6
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration (PubMed:24003225).
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

References

Kiefer M.C.,et al.J. Biol. Chem. 266:9043-9049(1991).
Ehrenborg E.,et al.Mamm. Genome 10:376-380(1999).
Shimasaki S.,et al.Mol. Endocrinol. 5:938-948(1991).
Zapf J.,et al.J. Biol. Chem. 265:14892-14898(1990).
Roghani M.,et al.FEBS Lett. 255:253-258(1989).

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$ 467.50
Cat# ALS13104
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