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SDC1 / Syndecan 1 / CD138 Antibody (clone DL-101)

Mouse Monoclonal Antibody

     
  • IHC - SDC1 / Syndecan 1 / CD138 Antibody (clone DL-101) ALS13119
    Anti-CD138 antibody IHC of human prostate.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IHC-Fr, Flo
Primary Accession P18827
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names DL-101
Calculated MW 32kDa
Dilution IHC-Fr, IHC-P (20 µg/ml),
Additional Information
Gene ID 6382
Other Names Syndecan-1, SYND1, CD138, SDC1, SDC
Reconstitution & Storage Store at 4°C, avoid repeated freeze thaw cycles.
PrecautionsSDC1 / Syndecan 1 / CD138 Antibody (clone DL-101) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDC1 (HGNC:10658)
Synonyms SDC
Function Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein. Secreted Secreted, extracellular exosome Note=Shedding of the ectodomain produces a soluble form
Tissue Location Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts (at protein level) (PubMed:36213313).
Research Areas
Citations (0)
citation

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Background

Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

References

Lories V.,et al.J. Biol. Chem. 267:1116-1122(1992).
Mali M.,et al.J. Biol. Chem. 265:6884-6889(1990).
Mennerich D.,et al.Eur. J. Cancer 40:1373-1382(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS13119
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