|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||Protein Shroom2, Apical-like protein, Protein APXL, SHROOM2, APXL|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||SHROOM2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity).|
|Cellular Location||Apical cell membrane. Cell junction, tight junction. Cytoplasm, cytoskeleton. Note=Associates with cortical F-actin|
|Tissue Location||Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity).
Schiaffino V.M.,et al.Hum. Mol. Genet. 4:373-382(1995).
Ross M.T.,et al.Nature 434:325-337(2005).
Hagens O.,et al.BMC Cell Biol. 7:18-18(2006).
Rigbolt K.T.,et al.Sci. Signal. 4:RS3-RS3(2011).
Sjoeblom T.,et al.Science 314:268-274(2006).
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