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BAK1 / BAK Antibody

Rabbit Polyclonal Antibody

     
  • WB - BAK1 / BAK Antibody ALS13130
    Sample (30 ug of whole cell lysate).
  • IHC - BAK1 / BAK Antibody ALS13130
    Anti-BAK1 / BAK antibody IHC of human breast.
  • IHC - BAK1 / BAK Antibody ALS13130
    Anti-BAK1 / BAK antibody IHC of human liver, bile duct.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q16611
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 23kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 578
Other Names Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like protein 7, Bcl2-L-7, BAK1, BAK, BCL2L7, CDN1
Target/Specificity Human BAK1.
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsBAK1 / BAK Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BAK1
Synonyms BAK, BCL2L7, CDN1
Function In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
Cellular Location Mitochondrion membrane; Single-pass membrane protein
Tissue Location Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle
Volume 50 µl
Research Areas
Citations (0)

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Background

In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.

References

Farrow S.N.,et al.Nature 374:731-733(1995).
Chittenden T.,et al.Nature 374:733-736(1995).
Kiefer M.C.,et al.Nature 374:736-739(1995).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).

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$ 395.00
Cat# ALS13130
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