|Application ||WB, IHC-P, IF, ICC|
|Dilution||IF (1:100-1:200), IHC-P (10 µg/ml), WB (1:500-1:3000)|
|Other Names||Fanconi anemia group C protein, Protein FACC, FANCC, FAC, FACC|
|Target/Specificity||Human and mouse FANCC.|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||FANCC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.|
|Cellular Location||Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic|
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Provided below are standard protocols that you may find useful for product applications.
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
Strathdee C.A.,et al.Nature 356:763-767(1992).
Strathdee C.A.,et al.Nature 358:434-434(1992).
Gibson R.A.,et al.Hum. Mol. Genet. 2:35-38(1993).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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