|Application ||WB, IHC-P, E|
|Dilution||IHC-P (1:200), WB (1:500-1:2000),|
|Other Names||Betaine--homocysteine S-methyltransferase 1, 188.8.131.52, BHMT|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||BHMT Antibody (clone 8C11H5) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.|
|Tissue Location||Found exclusively in liver and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.
Garrow T.A.,et al.J. Biol. Chem. 271:22831-22838(1996).
Park E.I.,et al.J. Biol. Chem. 274:7816-7824(1999).
Sunden S.L.F.,et al.Arch. Biochem. Biophys. 345:171-174(1997).
Millian N.S.,et al.Arch. Biochem. Biophys. 356:93-98(1998).
Evans J.C.,et al.Structure 10:1159-1171(2002).
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