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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CD80 Antibody (clone 2A2)   

CD80 Antibody (clone 2A2)

Mouse Monoclonal Antibody

     
  • IF - CD80 Antibody (clone 2A2) ALS13164
    Confocal immunofluorescence of BCBL-1 cells using anti-CD80 monoclonal antibody(green), showing...
  • IHC - CD80 Antibody (clone 2A2) ALS13164
    Anti-CD80 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF, E
Primary Accession P33681
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2A2
Calculated MW 33kDa
Dilution IF (1:200-1:1000), IHC-P (1:200),
Additional Information
Gene ID 941
Other Names T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD80, CD80, CD28LG, CD28LG1, LAB7
Target/Specificity Human CD80
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCD80 Antibody (clone 2A2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD80
Synonyms CD28LG, CD28LG1, LAB7
Function Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on activated B-cells, macrophages and dendritic cells
Research Areas
Citations (0)

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Background

Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.

References

Freeman G.J.,et al.J. Immunol. 143:2714-2722(1989).
Selvakumar A.,et al.Immunogenetics 36:175-181(1992).
Kakoulidou M.,et al.Scand. J. Immunol. 66:529-537(2007).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Freeman G.J.,et al.J. Exp. Med. 174:625-631(1991).

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$ 395.00
Cat# ALS13164
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