REG1A Antibody (clone 1A4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IF, E |
---|---|
Primary Accession | P05451 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1A4 |
Calculated MW | 19kDa |
Dilution | ELISA (1:10000), IF (1:200-1:1000), IHC-P (1:200) |
Gene ID | 5967 |
---|---|
Other Names | Lithostathine-1-alpha, Islet cells regeneration factor, ICRF, Islet of Langerhans regenerating protein, REG, Pancreatic stone protein, PSP, Pancreatic thread protein, PTP, Regenerating islet-derived protein 1-alpha, REG-1-alpha, Regenerating protein I alpha, REG1A, PSPS, PSPS1, REG |
Target/Specificity | Human REG1A |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | REG1A Antibody (clone 1A4) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | REG1A |
---|---|
Synonyms | PSPS, PSPS1, REG |
Function | Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. |
Cellular Location | Secreted. |
Tissue Location | In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients. |
Volume | 50 µl |
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Background
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
References
Terazono K.,et al.J. Biol. Chem. 263:2111-2114(1988).
Watanabe T.,et al.J. Biol. Chem. 265:7432-7439(1990).
Giorgi D.,et al.J. Clin. Invest. 84:100-106(1989).
Boonyasrisawat W.,et al.Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
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