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WNT1 Antibody (clone 10C8)

Mouse Monoclonal Antibody

     
  • IF - WNT1 Antibody (clone 10C8) ALS13171
    Figure3: Confocal immunofluorescence of HeLa (left) and 3T3-L1 (right) cells using WNT1 mouse...
  • IHC - WNT1 Antibody (clone 10C8) ALS13171
    Anti-WNT1 antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E, Flo
Primary Accession P04628
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Clone Names 10C8
Calculated MW 41kDa
Dilution ELISA (1:10000), Flo (1:200-1:400), IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000)
Additional Information
Gene ID 7471
Other Names Proto-oncogene Wnt-1, Proto-oncogene Int-1 homolog, WNT1, INT1
Target/Specificity Human WNT1
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsWNT1 Antibody (clone 10C8) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT1
Synonyms INT1
Function Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development.
Cellular Location Secreted, extracellular space, extracellular matrix
Volume 50 µl
Research Areas
Citations (0)

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Background

Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development.

References

van Ooyen A.,et al.EMBO J. 4:2905-2909(1985).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Doubravska L.,et al.Cell. Signal. 23:837-848(2011).
Keupp K.,et al.Am. J. Hum. Genet. 92:565-574(2013).

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$ 395.00
Cat# ALS13171
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