|Reactivity||Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Horse, Bovine, Dog|
|Dilution||IHC-P (3.75 µg/ml)|
|Other Names||Short transient receptor potential channel 1, TrpC1, Transient receptor protein 1, TRP-1, TRPC1, TRP1|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||TRPC1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Seems to be ubiquitous.|
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Provided below are standard protocols that you may find useful for product applications.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Zhu X.,et al.FEBS Lett. 373:193-198(1995).
Wes P.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:9652-9656(1995).
Zitt C.,et al.Neuron 16:1189-1196(1996).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lockwich T.P.,et al.J. Biol. Chem. 275:11934-11942(2000).
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