TRPC1 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P48995 |
Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Horse, Bovine, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 91kDa |
Dilution | IHC-P (3.75 µg/ml) |
Gene ID | 7220 |
---|---|
Other Names | Short transient receptor potential channel 1, TrpC1, Transient receptor protein 1, TRP-1, TRPC1, TRP1 |
Target/Specificity | Human TRPC1. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | TRPC1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TRPC1 |
---|---|
Synonyms | TRP1 |
Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | Seems to be ubiquitous. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
References
Zhu X.,et al.FEBS Lett. 373:193-198(1995).
Wes P.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:9652-9656(1995).
Zitt C.,et al.Neuron 16:1189-1196(1996).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lockwich T.P.,et al.J. Biol. Chem. 275:11934-11942(2000).
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