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I-FABP / FABP2 Antibody (clone 9A9B7B3)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E, FC |
|---|---|
| Primary Accession | P12104 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 9A9B7B3 |
| Calculated MW | 15kDa |
| Dilution | Flo (1:200-1:400), IF (1:200-1:1000), IHC-P (1:100), WB (1:500-1:2000) , |
| Gene ID | 2169 |
|---|---|
| Other Names | Fatty acid-binding protein, intestinal, Fatty acid-binding protein 2, Intestinal-type fatty acid-binding protein, I-FABP, FABP2, FABPI |
| Target/Specificity | Human FABP2 |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | I-FABP / FABP2 Antibody (clone 9A9B7B3) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FABP2 |
|---|---|
| Synonyms | FABPI |
| Function | FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. |
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Provided below are standard protocols that you may find useful for product applications.
Background
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
References
Sweetser D.A.,et al.J. Biol. Chem. 262:16060-16071(1987).
Hillier L.W.,et al.Nature 434:724-731(2005).
Pelsers M.M.A.L.,et al.Clin. Biochem. 36:529-535(2003).
Darimont C.,et al.Am. J. Physiol. 276:G606-G612(1999).
Rajabzadeh M.,et al.Biochemistry 42:12192-12199(2003).
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