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CSF1 / MCSF Antibody (clone 2D10)

Mouse Monoclonal Antibody

     
  • IHC - CSF1 / MCSF Antibody (clone 2D10) ALS13186
    Anti-CSF1 / MCSF antibody IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P09603
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2D10
Calculated MW 60kDa
Dilution IHC-P (1:200), WB (1:500-1:2000),
Additional Information
Gene ID 1435
Other Names Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, Lanimostim, Processed macrophage colony-stimulating factor 1, CSF1
Target/Specificity Human CSF1
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCSF1 / MCSF Antibody (clone 2D10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSF1
Function Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Cellular Location Cell membrane; Single-pass type I membrane protein
Volume 50 µl
Research Areas
Citations (0)

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Background

Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

References

Kawasaki E.S.,et al.Science 230:291-296(1985).
Wong G.G.,et al.Science 235:1504-1508(1987).
Cerretti D.P.,et al.Mol. Immunol. 25:761-770(1988).
Takahashi M.,et al.Biochem. Biophys. Res. Commun. 161:892-901(1989).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS13186
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