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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   VCAM1 / CD106 Antibody (clone 6G9)   

VCAM1 / CD106 Antibody (clone 6G9)

Mouse Monoclonal Antibody

     
  • IHC - VCAM1 / CD106 Antibody (clone 6G9) ALS13207
    Anti-VCAM1 antibody IHC of human colon, adipocytes.
  • IHC - VCAM1 / CD106 Antibody (clone 6G9) ALS13207
    Anti-VCAM1 antibody IHC of human placenta.
  • IHC - VCAM1 / CD106 Antibody (clone 6G9) ALS13207
    Anti-VCAM1 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P19320
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6G9
Calculated MW 81kDa
Dilution IHC-P (1:200), WB (1:500-1:2000),
Additional Information
Gene ID 7412
Other Names Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, VCAM1, L1CAM
Target/Specificity Human VCAM1
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsVCAM1 / CD106 Antibody (clone 6G9) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VCAM1
Synonyms L1CAM
Function Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue
Volume 50 µl
Research Areas
Citations (0)

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Background

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

References

Osborn L.,et al.Cell 59:1203-1211(1989).
Polte T.,et al.Nucleic Acids Res. 18:5901-5901(1990).
Hession C.,et al.J. Biol. Chem. 266:6682-6685(1991).
Cybulsky M.I.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:7859-7863(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS13207
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