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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   MUM1 Antibody (clone 4G10)   

MUM1 Antibody (clone 4G10)

Mouse Monoclonal Antibody

     
  • IHC - MUM1 Antibody (clone 4G10) ALS13208
    Anti-MUM1 antibody IHC of human small intestine, myenteric plexus.
  • IHC - MUM1 Antibody (clone 4G10) ALS13208
    Anti-MUM1 antibody IHC of human placenta.
  • IHC - MUM1 Antibody (clone 4G10) ALS13208
    Anti-MUM1 antibody IHC of human uterus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q2TAK8
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4G10
Calculated MW 79kDa
Dilution IHC-P (1:200), WB (1:500-1:2000),
Additional Information
Gene ID 84939
Other Names PWWP domain-containing protein MUM1, Mutated melanoma-associated antigen 1, MUM-1, Protein expandere, MUM1, EXPAND1
Target/Specificity Human MUM1
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsMUM1 Antibody (clone 4G10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MUM1
Synonyms EXPAND1
Function Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Cellular Location Nucleus. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1
Volume 50 µl
Research Areas
Citations (0)

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Background

Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

References

Grimwood J.,et al.Nature 428:529-535(2004).
Coulie P.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:7976-7980(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Huen M.S.,et al.Mol. Cell 37:854-864(2010).

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$ 395.00
Cat# ALS13208
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