|Reactivity||Human, Mouse, Monkey|
|Dilution||IHC-P (3.75 µg/ml)|
|Other Names||3-oxo-5-alpha-steroid 4-dehydrogenase 1, 126.96.36.199, SR type 1, Steroid 5-alpha-reductase 1, S5AR 1, SRD5A1|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||5-Alpha Reductase / SRD5A1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.|
|Cellular Location||Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Liver and prostate (at a low level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Andersson S.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:3640-3644(1990).
Jenkins E.P.,et al.Genomics 11:1102-1112(1991).
Yu W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.