|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Monkey, Pig, Chicken, Horse, Xenopus, Bovine, Dog|
|Dilution||IHC-P (3.75 µg/ml)|
|Other Names||Clathrin heavy chain 1, Clathrin heavy chain on chromosome 17, CLH-17, CLTC, CLH17, CLTCL2, KIAA0034|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||CLTC / Clathrin Heavy Chain Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CLH17, CLTCL2, KIAA0034|
|Function||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.|
|Cellular Location||Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Melanosome. Note=Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
Nomura N.,et al.DNA Res. 1:27-35(1994).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Dodge G.R.,et al.Genomics 11:174-178(1991).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
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