|Dilution||IHC-P (5 µg/ml)|
|Other Names||Tumor necrosis factor ligand superfamily member 13, A proliferation-inducing ligand, APRIL, TNF- and APOL-related leukocyte expressed ligand 2, TALL-2, TNF-related death ligand 1, TRDL-1, CD256, TNFSF13, APRIL, TALL2, ZTNF2|
|Target/Specificity||Human TNFSF13 / APRIL. This antibody is expected to recognize all isoforms (alpha, beta, gamma: NP_003799.1; NP_742084.1; NP_742085.1). This antibody also cross-reacts with human, mouse and dog TNFSF12-TNFSF13 protein (GeneID: 407977, 619441, 479484; ...|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||TNFSF13 / APRIL Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||APRIL, TALL2, ZTNF2|
|Function||Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.|
|Tissue Location||Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages|
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Provided below are standard protocols that you may find useful for product applications.
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Hahne M.,et al.J. Exp. Med. 188:1185-1190(1998).
Shu H.-B.,et al.J. Leukoc. Biol. 65:680-683(1999).
Farrah T.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Kelly K.A.,et al.Cancer Res. 60:1021-1027(2000).
Pradet-Balade B.,et al.EMBO J. 21:5711-5720(2002).
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