|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||CAD protein, Glutamine-dependent carbamoyl-phosphate synthase, 22.214.171.124, Aspartate carbamoyltransferase, 126.96.36.199, Dihydroorotase, 188.8.131.52, CAD|
|Target/Specificity||Human CAD. Predicted cross-reactivity based on amino acid sequence homology: mouse (92%), rat (92%).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||CAD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).|
|Cellular Location||Cytoplasm. Nucleus. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
Iwahana H.,et al.Biochem. Biophys. Res. Commun. 219:249-255(1996).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (FEB-2008) to UniProtKB.
Davidson J.N.,et al.DNA Cell Biol. 9:667-676(1990).
Zimmermann B.H.,et al.Biochemistry 34:7038-7046(1995).
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