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VRL1 / TRPV2 Antibody

Rabbit Polyclonal Antibody

     
  • WB - VRL1 / TRPV2 Antibody ALS13244
    Sample(30 g of whole cell lysate). A: A431. B: Raji. 7.5% SDS PAGE. TRPV2 antibody diluted at 1:500.
  • WB - VRL1 / TRPV2 Antibody ALS13244
    Sample (30 ug of whole cell lysate).
  • IHC - VRL1 / TRPV2 Antibody ALS13244
    Anti-TRPV2 antibody IHC of human small intestine, submucosal plexus.
  • IHC - VRL1 / TRPV2 Antibody ALS13244
    Anti-TRPV2 antibody IHC of human lung.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q9Y5S1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 86kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 51393
Other Names Transient receptor potential cation channel subfamily V member 2, TrpV2, Osm-9-like TRP channel 2, OTRPC2, Vanilloid receptor-like protein 1, VRL-1, TRPV2, VRL
Target/Specificity Human and mouse VRL1.
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsVRL1 / TRPV2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRPV2
Synonyms VRL
Function Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasm Melanosome. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Volume 100 µl
Research Areas
Citations (0)

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Background

Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.

References

Caterina M.J.,et al.Nature 398:436-441(1999).
Garcia R.L.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Kelsell R.E.,et al.Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 395.00
Cat# ALS13244
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