|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||Glutamyl aminopeptidase, EAP, 188.8.131.52, Aminopeptidase A, AP-A, Differentiation antigen gp160, CD249, ENPEP|
|Target/Specificity||Human Glutamyl aminopeptidase. Predicted cross-reactivity based on amino acid sequence homology: mouse (85%), rat (86%), bovine (89%), pig (90%).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||ENPEP / Aminopeptidase A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues|
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Provided below are standard protocols that you may find useful for product applications.
Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
Nanus D.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:7069-7073(1993).
Li L.,et al.Genomics 17:657-664(1993).
Hillier L.W.,et al.Nature 434:724-731(2005).
Liu T.,et al.J. Proteome Res. 4:2070-2080(2005).
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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