|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB|
|Target/Specificity||Human Rho GDI2. Predicted cross-reactivity based on amino acid sequence homology: mouse (90%), rat (89%), bovine (93%).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||GDI2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Asada M.,et al.Submitted (APR-1993) to the EMBL/GenBank/DDBJ databases.
Sedlacek Z.,et al.Mamm. Genome 9:78-80(1998).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
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