CACNG5 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q9UF02 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 31kDa |
Dilution | IHC-P (10 µg/ml), WB (1:500-1:3000), |
Gene ID | 27091 |
---|---|
Other Names | Voltage-dependent calcium channel gamma-5 subunit, Neuronal voltage-gated calcium channel gamma-5 subunit, Transmembrane AMPAR regulatory protein gamma-5, TARP gamma-5, CACNG5 |
Target/Specificity | Human CACNG5. Predicted cross-reactivity based on amino acid sequence homology: mouse (91%), rat (91%). |
Reconstitution & Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
Precautions | CACNG5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CACNG5 |
---|---|
Function | Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). |
Cellular Location | Membrane; Multi-pass membrane protein. Postsynaptic density membrane |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).
References
Burgess D.L.,et al.Genome Res. 9:1204-1213(1999).
Chu P.-J.,et al.Gene 280:37-48(2001).
Moss F.J.,et al.EMBO J. 21:1514-1523(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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