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ARVCF Antibody (clone 5D2)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O00192 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 5D2 |
| Calculated MW | 105kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 421 |
|---|---|
| Other Names | Armadillo repeat protein deleted in velo-cardio-facial syndrome, ARVCF |
| Reconstitution & Storage | Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
| Precautions | ARVCF Antibody (clone 5D2) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARVCF (HGNC:728) |
|---|---|
| Function | Contributes to the regulation of alternative splicing of pre- mRNAs. |
| Cellular Location | Cell junction, adherens junction. Nucleus. Cytoplasm Note=In heart, localizes at area composita, the mixed-type junctional structure composed of both desmosomal and adherens junctional proteins {ECO:0000250|UniProtKB:B4F7F3} |
| Tissue Location | Found in all the examined tissues including heart, brain, liver and kidney. Found at low level in lung. Expressed in dermal connective tissue, salivary gland duct and in the corneal layer (at protein level) (PubMed:30479852). Expressed in arrector pili muscle (at protein level) (PubMed:29034528). High levels detected in epithelial cells with lower levels found in fibroblasts and T lymphocytes (PubMed:10725230). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in protein-protein interactions at adherens junctions.
References
Sirotkin H.,et al.Genomics 41:75-83(1997).
Dunham I.,et al.Nature 402:489-495(1999).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Stenzel N.,et al.J. Cell Sci. 122:3374-3384(2009).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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