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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLIC1 / NCC27 Antibody (clone 3F9)   

CLIC1 / NCC27 Antibody (clone 3F9)

Mouse Monoclonal Antibody

     
  • WB - CLIC1 / NCC27 Antibody (clone 3F9) ALS13292
    CLIC1 monoclonal antibody, clone 3F9 Western blot of CLIC1 expression in 293.
  • WB - CLIC1 / NCC27 Antibody (clone 3F9) ALS13292
    Western blot of CLIC1 expression in transfected 293T cell line by CLIC1 monoclonal antibody,...
  • IHC - CLIC1 / NCC27 Antibody (clone 3F9) ALS13292
    Anti-CLIC1 antibody IHC of human breast.
  • IHC - CLIC1 / NCC27 Antibody (clone 3F9) ALS13292
    Anti-CLIC1 antibody IHC of human pancreas.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O00299
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3F9
Calculated MW 27kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 1192
Other Names Chloride intracellular channel protein 1, Chloride channel ABP, Nuclear chloride ion channel 27, NCC27, Regulatory nuclear chloride ion channel protein, hRNCC, CLIC1, G6, NCC27
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsCLIC1 / NCC27 Antibody (clone 3F9) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLIC1
Synonyms G6, NCC27
Function Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.
Cellular Location Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain
Tissue Location Expression is prominent in heart, placenta, liver, kidney and pancreas.
Research Areas
Citations (0)

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Background

Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.

References

Valenzuela S.M.,et al.J. Biol. Chem. 272:12575-12582(1997).
Noh Y.H.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Chuang J.Z.,et al.J. Neurosci. 19:2919-2928(1999).
Ribas G.,et al.J. Immunol. 163:278-287(1999).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS13292
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