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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CRYM Antibody (clone 6B3)   

CRYM Antibody (clone 6B3)

Mouse Monoclonal Antibody

     
  • WB - CRYM Antibody (clone 6B3) ALS13294
    CRYM monoclonal antibody clone 6B3 Western blot of CRYM expression in Jurkat.
  • IHC - CRYM Antibody (clone 6B3) ALS13294
    Anti-CRYM antibody IHC of human brain, cortex.
  • IHC - CRYM Antibody (clone 6B3) ALS13294
    Anti-CRYM antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q14894
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6B3
Calculated MW 34kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 1428
Other Names Ketimine reductase mu-crystallin, 1.5.1.25, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsCRYM Antibody (clone 6B3) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRYM
Synonyms THBP
Function Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.
Cellular Location Cytoplasm.
Tissue Location Expressed in neural tissue, muscle and kidney.
Research Areas
Citations (0)

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Background

Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.

References

Segovia L.,et al.Mol. Vis. 3:9-9(1997).
Vie M.-P.,et al.Mol. Endocrinol. 11:1728-1736(1997).
Sperbeck S.J.,et al.Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
Loftus B.J.,et al.Genomics 60:295-308(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 450.00
Cat# ALS13294
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