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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GBP1 Antibody (clone 4D10)   

GBP1 Antibody (clone 4D10)

Mouse Monoclonal Antibody

     
  • IHC - GBP1 Antibody (clone 4D10) ALS13308
    Anti-GBP1 antibody IHC of human tonsil.
  • IHC - GBP1 Antibody (clone 4D10) ALS13308
    Anti-GBP1 antibody IHC of human uterus.
  • WB - GBP1 Antibody (clone 4D10) ALS13308
    Western analysis of human spleen lysate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P32455
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4D10
Calculated MW 68kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 2633
Other Names Interferon-induced guanylate-binding protein 1, GTP-binding protein 1, GBP-1, HuGBP-1, Guanine nucleotide-binding protein 1, GBP1
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsGBP1 Antibody (clone 4D10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GBP1
Function Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Cellular Location Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor
Research Areas
Citations (0)

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Background

Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

References

Cheng Y.-S.E.,et al.Mol. Cell. Biol. 11:4717-4725(1991).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS13308
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