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GSTA3 Antibody (clone 1F11)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q16772 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 1F11 |
| Calculated MW | 25kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 2940 |
|---|---|
| Other Names | Glutathione S-transferase A3, 2.5.1.18, GST class-alpha member 3, Glutathione S-transferase A3-3, GSTA3 |
| Reconstitution & Storage | Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
| Precautions | GSTA3 Antibody (clone 1F11) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GSTA3 (HGNC:4628) |
|---|---|
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. Has substantial activity toward aflatoxin B1-8,9-epoxide (By similarity). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)- pregnene-3,20-dione, precursors to testosterone and progesterone, respectively.
References
Suzuki T.,et al.Genomics 18:680-686(1993).
Johansson A.-S.,et al.J. Biol. Chem. 276:33061-33065(2001).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Board P.G.,et al.Biochem. J. 330:827-831(1998).
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