HCLS1 Antibody (clone 2A8)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P14317 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2A8 |
Calculated MW | 54kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 3059 |
---|---|
Other Names | Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1 |
Reconstitution & Storage | Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
Precautions | HCLS1 Antibody (clone 2A8) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HCLS1 |
---|---|
Synonyms | HS1 |
Function | Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. |
Cellular Location | Membrane; Peripheral membrane protein. Cytoplasm. Mitochondrion |
Tissue Location | Expressed only in tissues and cells of hematopoietic origin |
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Provided below are standard protocols that you may find useful for product applications.
Background
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
References
Kitamura D.,et al.Nucleic Acids Res. 17:9367-9379(1989).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
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