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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HCLS1 Antibody (clone 2A8)   

HCLS1 Antibody (clone 2A8)

Mouse Monoclonal Antibody

     
  • WB - HCLS1 Antibody (clone 2A8) ALS13326
    HCLS1 monoclonal antibody, clone 2A8 Western blot of HCLS1 expression in K-562.
  • IHC - HCLS1 Antibody (clone 2A8) ALS13326
    Anti-HCLS1 antibody IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P14317
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2A8
Calculated MW 54kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 3059
Other Names Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsHCLS1 Antibody (clone 2A8) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HCLS1
Synonyms HS1
Function Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Cellular Location Membrane; Peripheral membrane protein Cytoplasm. Mitochondrion
Tissue Location Expressed only in tissues and cells of hematopoietic origin
Research Areas
Citations (0)

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Background

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

References

Kitamura D.,et al.Nucleic Acids Res. 17:9367-9379(1989).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).

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$ 450.00
Cat# ALS13326
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