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FOXP2 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O15409 |
| Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 80kDa |
| Dilution | ELISA (1:64000), IHC-P (2.5 µg/ml), WB (0.3-1 µg/ml) |
| Gene ID | 93986 |
|---|---|
| Other Names | Forkhead box protein P2, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein, FOXP2, CAGH44, TNRC10 |
| Target/Specificity | Human FOXP2. This antibody is expected to recognize isoform I (NP_055306.1), isoform II (NP_683696.2), isoform IV (NP_683698.2) and isoform V (NP_001166237.1). |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | FOXP2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXP2 |
|---|---|
| Synonyms | CAGH44, TNRC10 |
| Function | Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language. |
| Cellular Location | Nucleus. |
| Tissue Location | Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
References
Lai C.S.L.,et al.Nature 413:519-523(2001).
Bruce H.A.,et al.Hum. Genet. 111:136-144(2002).
Vincent J.B.,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Guo J.H.,et al.Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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