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FOXP2 Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - FOXP2 Antibody (Internal) ALS13332
    Anti-FOXP2 antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O15409
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 80kDa
Dilution ELISA (1:64000), IHC-P (2.5 µg/ml), WB (0.3-1 µg/ml)
Additional Information
Gene ID 93986
Other Names Forkhead box protein P2, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein, FOXP2, CAGH44, TNRC10
Target/Specificity Human FOXP2. This antibody is expected to recognize isoform I (NP_055306.1), isoform II (NP_683696.2), isoform IV (NP_683698.2) and isoform V (NP_001166237.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsFOXP2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXP2
Synonyms CAGH44, TNRC10
Function Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
Cellular Location Nucleus.
Tissue Location Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung
Citations (0)

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Background

Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.

References

Lai C.S.L.,et al.Nature 413:519-523(2001).
Bruce H.A.,et al.Hum. Genet. 111:136-144(2002).
Vincent J.B.,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Guo J.H.,et al.Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS13332
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