|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Sheep, Horse, Bovine, Dog|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.5-1.5 µg/ml)|
|Other Names||Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha, THRA, EAR7, ERBA1, NR1A1, THRA1, THRA2|
|Target/Specificity||Human THRA. This antibody is expected to recognize both reported isoforms (NP_955366.1; NP_003241.2). This antibody is not expected to cross-react to THRB.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||THRA / THR Alpha Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||EAR7, ERBA1, NR1A1, THRA1, THRA2|
|Function||Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.|
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Provided below are standard protocols that you may find useful for product applications.
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Laudet V.,et al.Nucleic Acids Res. 19:1105-1112(1991).
Miyajima N.,et al.Cell 57:31-39(1989).
Nakai A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:2781-2785(1988).
Pfahl M.,et al.Nucleic Acids Res. 15:9613-9613(1987).
Nakai A.,et al.Mol. Endocrinol. 2:1087-1092(1988).
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