|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Sheep, Horse, Bovine, Dog|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.5-1.5 µg/ml)|
|Other Names||Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha, THRA, EAR7, ERBA1, NR1A1, THRA1, THRA2|
|Target/Specificity||Human THRA. This antibody is expected to recognize both reported isoforms (NP_955366.1; NP_003241.2). This antibody is not expected to cross-react to THRB.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||THRA / THR Alpha Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||EAR7, ERBA1, NR1A1, THRA1, THRA2|
|Function||Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Laudet V.,et al.Nucleic Acids Res. 19:1105-1112(1991).
Miyajima N.,et al.Cell 57:31-39(1989).
Nakai A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:2781-2785(1988).
Pfahl M.,et al.Nucleic Acids Res. 15:9613-9613(1987).
Nakai A.,et al.Mol. Endocrinol. 2:1087-1092(1988).
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