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MSI1 / Musashi 1 Antibody (clone 3F2)

Mouse Monoclonal Antibody

     
  • WB - MSI1 / Musashi 1 Antibody (clone 3F2) ALS13357
    MSI1 monoclonal antibody clone 3F2 Western blot of MSI1 expression in IMR-32.
  • IF - MSI1 / Musashi 1 Antibody (clone 3F2) ALS13357
    Immunofluorescence of monoclonal antibody to MSI1 on HeLa cell (antibody concentration 10 ug/ml).
  • IHC - MSI1 / Musashi 1 Antibody (clone 3F2) ALS13357
    Anti-MSI1 antibody IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession O43347
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3F2
Calculated MW 39kDa
Dilution IF (10 µg/ml), IHC-P (10 µg/ml),
Additional Information
Gene ID 4440
Other Names RNA-binding protein Musashi homolog 1, Musashi-1, MSI1
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsMSI1 / Musashi 1 Antibody (clone 3F2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSI1
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Cellular Location Cytoplasm. Nucleus
Tissue Location Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Research Areas
Citations (0)

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Background

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

References

Good P.,et al.Genomics 52:382-384(1998).
Scherer S.E.,et al.Nature 440:346-351(2006).
Shu H.-J.,et al.Biochem. Biophys. Res. Commun. 293:150-154(2002).
Okano H.,et al.J. Cell Sci. 115:1355-1359(2002).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).

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$ 450.00
Cat# ALS13357
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