|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Monkey|
|Dilution||ELISA (1:8000), IHC-P (3.75 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||ATP-binding cassette sub-family D member 4, PMP70-related protein, P70R, Peroxisomal membrane protein 1-like, PXMP1-L, Peroxisomal membrane protein 69, PMP69, ABCD4, PXMP1L|
|Target/Specificity||Human ABCD4. Reported variants represent identical protein: NP_064719.1 NP_064731.1 NP_064720.1 NP_064730.1|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||ABCD4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm.|
|Cellular Location||Peroxisome membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm.
Holzinger A.,et al.Biochem. Biophys. Res. Commun. 237:152-157(1997).
Holzinger A.,et al.FEBS Lett. 426:238-242(1998).
Shani N.,et al.Hum. Mol. Genet. 6:1925-1931(1997).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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