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RTKN / Rhotekin Antibody (clone 2E5)

Mouse Monoclonal Antibody

     
  • WB - RTKN / Rhotekin Antibody (clone 2E5) ALS13389
    RTKN monoclonal antibody clone 2E5 Western blot of RTKN expression in A-431.
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  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9BST9
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2E5
Calculated MW 63kDa
Dilution IHC-P (10-20 µg/ml)
Additional Information
Gene ID 6242
Other Names Rhotekin, RTKN (HGNC:10466), RTKN1
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsRTKN / Rhotekin Antibody (clone 2E5) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RTKN (HGNC:10466)
Synonyms RTKN1
Function Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
Tissue Location Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested Overexpressed in various cancer cell lines
Research Areas
Citations (0)
citation

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Background

Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.

References

Fu Q.,et al.Genomics 66:328-332(2000).
Reynaud C.,et al.J. Biol. Chem. 275:33962-33968(2000).
Hillier L.W.,et al.Nature 434:724-731(2005).
Liu C.-A.,et al.Oncogene 23:8731-8742(2004).
Ito H.,et al.Oncogene 24:7064-7072(2005).

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Discontinued
Cat# ALS13389
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