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CCNDBP1 / GCIP Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - CCNDBP1 / GCIP Antibody (C-Terminus) ALS13418
    Anti-CCNDBP1 / GCIP antibody IHC of human brain, cortex.
  • IHC - CCNDBP1 / GCIP Antibody (C-Terminus) ALS13418
    Anti-CCNDBP1 / GCIP antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O95273
Reactivity Human, Horse
Host Goat
Clonality Polyclonal
Calculated MW 40kDa
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml),
Additional Information
Gene ID 23582
Other Names Cyclin-D1-binding protein 1, Grap2 and cyclin-D-interacting protein, Human homolog of Maid, CCNDBP1, DIP1, GCIP, HHM
Target/Specificity Human CCNDBP1 / GCIP. This antibody is expected to recognise both human isoforms of this protein.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsCCNDBP1 / GCIP Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCNDBP1
Synonyms DIP1, GCIP, HHM
Function May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Ubiquitously expressed. Expression is down- regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Research Areas
Citations (0)

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Background

May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription.

References

Yao Y.,et al.Exp. Cell Res. 257:22-32(2000).
Terai S.,et al.Hepatology 32:357-366(2000).
Xia C.,et al.J. Biol. Chem. 275:20942-20948(2000).
Gao J.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).

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$ 395.00
Cat# ALS13418
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