Dipeptidylpeptidase 10 / DPP10 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q8N608 |
Reactivity | Human, Rabbit, Monkey, Pig, Horse, Bovine |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 91kDa |
Dilution | ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml) |
Gene ID | 57628 |
---|---|
Other Names | Inactive dipeptidyl peptidase 10, Dipeptidyl peptidase IV-related protein 3, DPRP-3, Dipeptidyl peptidase X, DPP X, Dipeptidyl peptidase-like protein 2, DPL2, DPP10, DPRP3, KIAA1492 |
Target/Specificity | Human DPP10. This antibody is expected to recognise both reported isoforms NP_065919.2 and NP_001004360.2. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | Dipeptidylpeptidase 10 / DPP10 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DPP10 |
---|---|
Synonyms | DPRP3, KIAA1492 |
Function | Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:15454437). Has no dipeptidyl aminopeptidase activity (PubMed:12662155). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q6NXK7, ECO:0000269|PubMed:14566338}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P42658} |
Tissue Location | Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands |
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Provided below are standard protocols that you may find useful for product applications.
Background
Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2.
References
Chen T.,et al.Adv. Exp. Med. Biol. 524:79-86(2003).
Qi S.Y.,et al.Biochem. J. 373:179-189(2003).
Allen M.,et al.Nat. Genet. 35:258-263(2003).
Takimoto K.,et al.Biochem. Biophys. Res. Commun. 348:1094-1100(2006).
Nagase T.,et al.DNA Res. 7:143-150(2000).
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